Clininal Medicine (Immunology), Ph.D.
Phone: (+66)2-470-7588 Office: RD1-A3-13, PDTI
Research focus: (Vaccine Development)
Porcine Reproductive and Respiratory Syndrome (PRRS) and Porcine Epidemic Diarrhea (PED) caused by PRRS virus (PRRSV) and PED virus (PEDV), respectively, are currently the most economically important diseases in swine industry worldwide as well as in Thailand. Therefore, a safe and effective vaccine is greatly needed to control the diseases.
Our current research is focused on development of PRRSV and PEDV vaccine candidates that can induce humoral response and cell-mediated response against PRRSV and PEDV. The new antigens are designed based on the genetic codes of PRRSV and PEDV variants currently circulating in Thailand. The new vaccines are developed based on DNA vaccine and viral-based vaccine technology. For viral-based vaccines, repilcation-defective adenovirus and Modified Vaccinia virus Ankara (MVA), whose safety profiles have been confirmed in humans and animals, are employed as vaccine delivery vehicles.
Additionally, we also aim to apply bioinformatics knowledge and tools to help design a novel vaccine antigen carrying highest capacity at inducing both humoral and cell-mediated immunity that can provide protection against PRRSV and PEDV infection.
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